APPARATUS AND METHODS FOR DRUG DELIVERY USING MICRONEEDLES

A microneedle has a proximal end portion and a distal end portion and defines a lumen. The proximal end portion is configured to be coupled to a cartridge to place the lumen in fluid communication with the cartridge. The proximal end portion includes a base surface that is configured to be placed in...

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Bibliographische Detailangaben
Hauptverfasser: Patel Samirkumar R, Edelhauser Henry F, Prausnitz Mark R, Zarnitsyn Vladimir G, Grossniklaus Hans
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A microneedle has a proximal end portion and a distal end portion and defines a lumen. The proximal end portion is configured to be coupled to a cartridge to place the lumen in fluid communication with the cartridge. The proximal end portion includes a base surface that is configured to be placed in contact with a surface of a target tissue. The distal end portion of the microneedle includes a beveled surface. The beveled surface defines a tip angle of less than about 20 degrees and a ratio of a bevel height to a bevel width of less than about 2.5.