INHIBITORS OF HIF PROLYL HYDROXYLASE

INHIBITORS OF HIF PROLYL HYDROXYLASE

The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such...

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Bibliographische Detailangaben
Hauptverfasser: LIU RONGQIANG, WANG LIPING, DUBOIS BYRON GABRIEL, GUIADEEN DEODIALSINGH, LIU PING, SINZ CHRISTOPHER, CAI JIAQIANG, CRESPO ALEJANDRO, KOTHANDARAMAN SHANKARAN, DU XIAOXING, QUAN WEIGUO
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.