TRIAZINE COMPOUNDS AS PI3 KINASE AND MTOR INHIBITORS
and R2, R4, and R6-9 are defined herein, and pharmaceutically acceptable salts and esters thereof. These compounds inhibit PI3 kinase and mTOR, and may be used to treat diseases mediated by PI3 kinase and mTOR, such as a variety of cancers. Methods for making and using the compounds of this inventio...
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| creator | CHEN Zecheng RICHARD David James DEHNHARDT Christoph Martin AYRAL-KALOUSTIAN Semiramis DOS SANTOS Osvaldo MANSOUR Tarek Suhayl VENKATESAN Aranapakam Mudumbai GOPALSAMY Ariamala VERHEIJEN Jeroen Cunera SHI Mengxiao ZASK Arie DELOS SANTOS Efren Guillermo KAPLAN Joshua Aaron CURRAN Kevin Joseph |
| description | and R2, R4, and R6-9 are defined herein, and pharmaceutically acceptable salts and esters thereof. These compounds inhibit PI3 kinase and mTOR, and may be used to treat diseases mediated by PI3 kinase and mTOR, such as a variety of cancers. Methods for making and using the compounds of this invention are disclosed. Various compositions containing the compounds of this invention are also disclosed. |
| format | Patent |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | TRIAZINE COMPOUNDS AS PI3 KINASE AND MTOR INHIBITORS |
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