SYNTHESIS OF 2,2,2-TRIFLUOROETHANETHIOL

SYNTHESIS OF 2,2,2-TRIFLUOROETHANETHIOL

A method of making CF3CH2SH, comprising a step of reacting CF3CH2X, wherein X is halide or tosylate, with MSH, where M is an alkali metal such as Na or K, to yield CF3CH2SH. More specifically, a method of making CF3CH2SH, a step of reacting CF3CH2CI with a molar excess of NaSH in a reaction medium o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Polsz Craig Alan, Srinivas Vijay R, Swan Dana Lee, Syvret Robert George
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:A method of making CF3CH2SH, comprising a step of reacting CF3CH2X, wherein X is halide or tosylate, with MSH, where M is an alkali metal such as Na or K, to yield CF3CH2SH. More specifically, a method of making CF3CH2SH, a step of reacting CF3CH2CI with a molar excess of NaSH in a reaction medium of one or more polar organic solvents at a temperature of from about 70 C to about 110 C for a time of from about 1 to about 5 hours.