LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS

or a pharmaceutically acceptable salt thereof, wherein R1-R4, L and X are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.

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Bibliographische Detailangaben
Hauptverfasser: Gamber Gabriel Grant, Zhao Junping, Bowman Keith, Zabawa Thomas, Wang Shuangxi, West Laura Ellen, Fazal Tanzina, Tichkule Ritesh Bhanudasji, Vargeese Chandra, Beckwith Rohan Eric John, Byers Crystal, Lee Cameron Chuck-munn, Baryza Jeremy Lee
Format: Patent
Sprache:eng
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Zusammenfassung:or a pharmaceutically acceptable salt thereof, wherein R1-R4, L and X are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.