DERIVATIVES OF 7-FLUORO-8-CHLORO-5H-DIBENZO [B,E,] [1,4] DIAZEPINE AND USE THEREOF

This present disclosure generally relates to medicine, and in particular to pharmacology and psychiatry, and discloses active agents and related methods of treatment which can be used for the treatment of treatment-resistant forms of schizophrenia. In some exemplary aspects, such treatments allow fo...

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Bibliographische Detailangaben
Hauptverfasser: ZAPOLSKI Maksim E, BENIASHVILI Allan G, MOROZOVA Margarita A
Format: Patent
Sprache:eng
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Zusammenfassung:This present disclosure generally relates to medicine, and in particular to pharmacology and psychiatry, and discloses active agents and related methods of treatment which can be used for the treatment of treatment-resistant forms of schizophrenia. In some exemplary aspects, such treatments allow for eliminating both the positive and negative symptoms of schizophrenia, and cognitive disorders, without causing severe side effects that limit their use, such as sedation, tachycardia, orthostatism, agranulocytosis and sialorrhea.