HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF

The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accum...

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Hauptverfasser: PURGATORIO Rosa, DENG Shixian, O'CONNOR Owen Anthony, LANDRY Donald W, ARANCIO Ottavio, FIORITO Jole, AMENGUAL Jennifer Effie
Format: Patent
Sprache:eng
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Zusammenfassung:The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.