Therapeutic Antibodies

A pharmaceutical comprising a therapeutic protein that binds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Frewin Mark Raymond, Gilliland Lisa Kim, Waldmann Herman, Simoes Da Silva Graca Luis Richardo
Format: Patent
Sprache:eng
Schlagworte:
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Beschreibung
Zusammenfassung:A pharmaceutical comprising a therapeutic protein that binds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.