Byosynthetic Production of Acyl Amino Acids

The present invention relates to a cell for producing acyl glycinateswherein the cell is genetically modified to comprise -at least a first genetic mutation that increases the expression relative to the wild type cell of an amino acid-N-acyl-transferase, -at least a second genetic mutation that incr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	DECKER NICOLE, OLFERT MAIK, ARTO NILS, HENNEMANN HANS-GEORG, SCHAFFER STEFFEN, GRAMMANN KATRIN, REINECKE LIV
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMES ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a cell for producing acyl glycinateswherein the cell is genetically modified to comprise -at least a first genetic mutation that increases the expression relative to the wild type cell of an amino acid-N-acyl-transferase, -at least a second genetic mutation that increases the expression relative to the wild type cell of an acyl-CoA synthetase, and -at least a third genetic mutation that decreases the expression relative to the wild type cell of at least one enzyme selected from the group consisting of an enzyme of the glycine cleavage system, glycine hydroxymethyltransferase (GlyA) and threoninealdolase (LtaE).