Crystalline Forms Of Pemetrexed Diacid And Processes For The Preparation Thereof

Crystalline Forms Of Pemetrexed Diacid And Processes For The Preparation Thereof

Provided are crystalline forms of N-[4-[2-(2-amino-4, 7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]ben-zoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.

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Bibliographische Detailangaben
Hauptverfasser: Pirkes Moran, Diulgheroff Nicola, Villa Marco, Pontiroli Alessandro, Aronhime Judith, Busolli Jonathan, Racz Csilla Nemethne
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Provided are crystalline forms of N-[4-[2-(2-amino-4, 7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]ben-zoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.