PROCESSING OF POLYNUCLEOTIDES

Methods and compositions for processing polynucleotides are provided according to some embodiments herein. In some embodiments, a sample is immobilized in a porous matrix, and non-polynucleotides are removed from the sample. In some embodiments, polynucleotides are labeled or enzymatically modified...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Saghbini Michael G, Stedman William, Hastie Alex R, Cao Han
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Methods and compositions for processing polynucleotides are provided according to some embodiments herein. In some embodiments, a sample is immobilized in a porous matrix, and non-polynucleotides are removed from the sample. In some embodiments, polynucleotides are labeled or enzymatically modified the matrix. In some embodiments, labeled or enzymatically modified polynucleotides are removed from the matrix for analysis.