SOLID PRODRUG FORMS OF 2'-CHLORO-2'-METHYL URIDINE FOR HCV

SOLID PRODRUG FORMS OF 2'-CHLORO-2'-METHYL URIDINE FOR HCV

Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shultz Clinton Scott, Mayes Benjamin Alexander, Ganga Sindhura, Sulliva-Bolyai John Zoltan, Moussa Adel M, Mayers Douglas Lytle, Zhou Xiao-Jian, Lee Alfred, Stewart Alistair James
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
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Beschreibung
Zusammenfassung:Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are solid forms of Compound I: (Compound I)