POLYMERIC SUBSTRATES WITH IMMOBILIZED ANTIBODIES AND METHOD OF PRODUCTION THEREOF

The present invention relates to biofunctional polymeric substrates product comprising immobilized antibodies that selective bind to antigens namely autologous growth factors and an inflammatory molecule, uses and method of production. The bio-functional polymeric substrate can be used in a quantifi...

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Hauptverfasser: MELEIRO ALVES DAS NEVES Nuno João, GONÇALVES DOS REIS Rui Luís, FREITAS SALAZAR DE OLIVEIRA Ana Catarina, PEREIRA MARTINS Albino Manuel
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to biofunctional polymeric substrates product comprising immobilized antibodies that selective bind to antigens namely autologous growth factors and an inflammatory molecule, uses and method of production. The bio-functional polymeric substrate can be used in a quantification method of antigens namely soluble growth factors, inflammatory molecules and hormones or the biofunctional polymeric substrate can be used to isolate extracellular vesicules. The biofunctional polymeric substrate can be also used in Tissue Engineering and Regenerative Medicine approaches, namely in bone and cartilage lesions, esophageal lesions, periodontal ligament reconstruction and skin lesions regeneration or treatment.