Sterile Emulsion Comprising a Stable Phosphorothioate Oligonucleotide

The present invention relates to a composition comprising a phosphorothioate oligonucleotide and at least one fatty acid and/or at least one emulsifying agent, wherein said composition is sterile and wherein said composition comprises an agent comprising a thiol group, preferably said composition is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Al-Mahmood Salman, Colin Sylvie, Steverlynck Celine, Bongaerts Maud
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a composition comprising a phosphorothioate oligonucleotide and at least one fatty acid and/or at least one emulsifying agent, wherein said composition is sterile and wherein said composition comprises an agent comprising a thiol group, preferably said composition is an ophthalmic composition; to a method for obtaining the same and to the therapeutic use thereof.