PEGYLATED GROWTH HORMONE ANTAGONISTS

A composition that is a human growth hormone receptor antagonist comprising human growth hormone receptor antagonist G120K, wherein at least one amino acid of human growth hormone receptor antagonist G120K has been mutated to cysteine; and a polytethylene glycol molecule (PEG) conjugated to each cys...

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Bibliographische Detailangaben
1. Verfasser: BRODY Richard S
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A composition that is a human growth hormone receptor antagonist comprising human growth hormone receptor antagonist G120K, wherein at least one amino acid of human growth hormone receptor antagonist G120K has been mutated to cysteine; and a polytethylene glycol molecule (PEG) conjugated to each cysteine residue in the human growth hormone receptor antagonist G120K mutant.