MESENCHYMAL STEM CELLS FOR THE TREATMENT OF CNS DISEASES

MESENCHYMAL STEM CELLS FOR THE TREATMENT OF CNS DISEASES

An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generatin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KADOURI Avinoam, BAR-ILAN Avihay, MELAMED Eldad, OFFEN Daniel, BAHAT-STROMZA Merav, SADAN Ofer
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.