COMPOSITIONS AND METHODS FOR DIAGNOSING, EVALUATING AND TREATING CANCER

The present invention relates to methods of determining a cancer treatment prognosis for a subject in need thereof by evaluating epigenetic and genetic changes within a tumor sample from the subject. The present invention further provides methods of treating cancer in a subject by evaluating epigene...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MEISSNER Alexander, WU Catherine Ju-Ying, LANDAU Dan-Avi, GETZ Gad, Clement Mark Kendell
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to methods of determining a cancer treatment prognosis for a subject in need thereof by evaluating epigenetic and genetic changes within a tumor sample from the subject. The present invention further provides methods of treating cancer in a subject by evaluating epigenetic and genetic changes within a tumor sample from the subject. In addition, the present invention provides methods of screening test agents to identify agents that decrease tumor cell plasticity.