PREPARATION OF MULTI-HAPTEN MUTANT G6PDH CONJUGATES AND THEIR USE FOR DETECTION OF MULTIPLE ANALYTES

The present invention relates to multi-hapten mutant G6PDH conjugates, methods of their preparation and their use for detection of multiple analytes. The compositions of the invention comprise different types of haptens (molecules) require to be immobilized into the G6PDH to make one multi-hapten-G6...

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Bibliographische Detailangaben
Hauptverfasser: Zheng Yi Feng, Morjana Nihmat, Hudson Linda, Yang Yali
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to multi-hapten mutant G6PDH conjugates, methods of their preparation and their use for detection of multiple analytes. The compositions of the invention comprise different types of haptens (molecules) require to be immobilized into the G6PDH to make one multi-hapten-G6PDH conjugate. Both thiol and amine functional groups on G6PDH are utilized for immobilization of different haptens.