ALLOSTERIC MODULATORS OF FACTOR XIa AS ANTICOAGULANT AGENTS

Compounds which allosterically modulate and/or inhibit factor XIa activity are provided, as are methods of their use. These compounds include i) sulfated gallolyl glucosides, ii) sulfated quinazolinones, and iii) sulfated inositol analogs. The compounds used as anticoagulant agents.

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Bibliographische Detailangaben
Hauptverfasser:	AL-HORANI Rami A, DESAI Umesh R, MEHTA Akul, KARUTURI Rajesh
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS
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Beschreibung
Zusammenfassung:	Compounds which allosterically modulate and/or inhibit factor XIa activity are provided, as are methods of their use. These compounds include i) sulfated gallolyl glucosides, ii) sulfated quinazolinones, and iii) sulfated inositol analogs. The compounds used as anticoagulant agents.