Biosynthetic Mint

A method for producing a menthol isomer is disclosed, comprising: (i) providing a microorganism modified to have increased expression of an ene reductase and one or more menthone dehydrogenase; (ii) contacting said microorganism, or a protein-containing extract thereof, with a biosynthetic precursor...

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Bibliographische Detailangaben
Hauptverfasser: Toogood Helen Susan, Gardiner John, Scrutton Nigel Shaun
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A method for producing a menthol isomer is disclosed, comprising: (i) providing a microorganism modified to have increased expression of an ene reductase and one or more menthone dehydrogenase; (ii) contacting said microorganism, or a protein-containing extract thereof, with a biosynthetic precursor of said menthol isomer; and (iii) maintaining the mixture of step (ii) under conditions suitable for biotransformation of said biosynthetic precursor to said menthol isomer.