METHOD FOR SUBTYPING LYMPHOMA TYPES BY MEANS OF EXPRESSION PROFILING

The invention is directed to methods for selecting a treatment option for an activated B cell-like diffuse large B cell lymphoma (ABC DLBCL) subject, a germinal center B cell-like diffuse large B cell lymphoma (GCB DLBCL) subject, a primary mediastinal B cell lymphoma (PMBL) subject, a Burkitt lymph...

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Hauptverfasser: Tubbs (Deceased) Raymond, Braziel Rita M, Rosenwald Andreas, Gascoyne Randy D, Scott David William, Rimsza Lisa, Wright George W, Williams Paul Michael, Lih Chih-Jian, Delabie Jan, Connors Joseph M, Smeland Erlend B, Staudt Louis M, Cook James Robert, Jaffe Elaine S, Weisenburger Dennis, Greiner Timothy C, Fu Kai, Chan Wing C, Guerri Elias Campo, Ott German
Format: Patent
Sprache:eng
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Zusammenfassung:The invention is directed to methods for selecting a treatment option for an activated B cell-like diffuse large B cell lymphoma (ABC DLBCL) subject, a germinal center B cell-like diffuse large B cell lymphoma (GCB DLBCL) subject, a primary mediastinal B cell lymphoma (PMBL) subject, a Burkitt lymphoma (BL) subject, or a mantle cell lymphoma (MCL) subject by analyzing digital gene expression data obtained from the subject, e.g., from a biopsy sample.