METHODS OF DIAGNOSING CANCER

The invention provides a method of diagnosing the presence of cancer in a subject by detecting the expression of a signal peptide-containing protein, wherein the method comprises: providing a biological sample from the subject; contacting the biological sample with a polypeptide which specifically b...

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Bibliographische Detailangaben
Hauptverfasser:	Reddy Roopa, Mathur Preete, Au-Young Janice, Murry Lynn E, LAL Preeti G
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides a method of diagnosing the presence of cancer in a subject by detecting the expression of a signal peptide-containing protein, wherein the method comprises: providing a biological sample from the subject; contacting the biological sample with a polypeptide which specifically binds to antibodies present in the biological sample, wherein the polypeptide is selected from the group consisting of a polypeptide comprising the amino acid sequence of SEQ ID NO:16 and a polypeptide having an amino acid sequence at least about 90% identical to the amino acid sequence of SEQ ID NO:16; detecting the presence of bound polypeptide in the biological sample; comparing the presence of bound polypeptide in the biological sample with the presence of bound polypeptide in a control sample; wherein a higher presence in the biological sample as compared to the control sample is correlated with the presence of cancer.