Binding Moieties Based On Shark IgNAR Domains

The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural featu...

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Bibliographische Detailangaben
Hauptverfasser: Hudson Peter, Varghese Joseph Noozhumurry, Carmichael Jennifer Ann, Henderson Kylie Anne, Griffiths Katherine Merne, Simmons David Peter, Streltsov Victor, Nuttall Stewart, Irving Robert Alexander, Barraclough Miles Mackay
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural features derived from IgNAR variable domains.