FC RECEPTOR BINDING PROTEINS

FC RECEPTOR BINDING PROTEINS

This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.

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Bibliographische Detailangaben
Hauptverfasser: Wood Clive, Bitonti Alan J, McDonnell Kevin A, Sato Aaron K, Dumont Jennifer, Viswanathan Malini, TenHoor Christopher, Ladner Robert Charles, Muruganandam Arumugam, McGivney James M, Liu Liming
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:This disclosure provides, inter alia, proteins that bind to FcRn, e.g., immunoglobulins that inhibit FcRn with high affinity and selectivity. The FcRn-binding proteins can be used to treat a variety of disorders including autoimmune disorders.