PROCESS FOR THE PREPARATION OF APIXABAN

PROCESS FOR THE PREPARATION OF APIXABAN

A crystalline Form N-1 of apixaban substantially free from one or more of: 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-car...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: DIWAKAR SANTOSH DEVIDAS, SUTHAR HITESHKUMAR NATWARLAL, SINGH KUMAR KAMLESH, KHERA BRIJ, NARODE SUNIL DNYANESHWAR
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator DIWAKAR SANTOSH DEVIDAS
SUTHAR HITESHKUMAR NATWARLAL
SINGH KUMAR KAMLESH
KHERA BRIJ
NARODE SUNIL DNYANESHWAR
description A crystalline Form N-1 of apixaban substantially free from one or more of: 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; or methyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate, relative to apixaban by area percentage of HPLC and having a mean particle size equal to or greater than 100 μm.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2016143894A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2016143894A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2016143894A13</originalsourceid><addsrcrecordid>eNrjZFAPCPJ3dg0OVnDzD1II8XBVCAhyDXAMcgzx9PdT8HdTcAzwjHB0cvTjYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxocFGBoZmhibGFpYmjobGxKkCAGyeJLM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PROCESS FOR THE PREPARATION OF APIXABAN</title><source>esp@cenet</source><creator>DIWAKAR SANTOSH DEVIDAS ; SUTHAR HITESHKUMAR NATWARLAL ; SINGH KUMAR KAMLESH ; KHERA BRIJ ; NARODE SUNIL DNYANESHWAR</creator><creatorcontrib>DIWAKAR SANTOSH DEVIDAS ; SUTHAR HITESHKUMAR NATWARLAL ; SINGH KUMAR KAMLESH ; KHERA BRIJ ; NARODE SUNIL DNYANESHWAR</creatorcontrib><description>A crystalline Form N-1 of apixaban substantially free from one or more of: 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; or methyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate, relative to apixaban by area percentage of HPLC and having a mean particle size equal to or greater than 100 μm.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20160526&amp;DB=EPODOC&amp;CC=US&amp;NR=2016143894A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20160526&amp;DB=EPODOC&amp;CC=US&amp;NR=2016143894A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DIWAKAR SANTOSH DEVIDAS</creatorcontrib><creatorcontrib>SUTHAR HITESHKUMAR NATWARLAL</creatorcontrib><creatorcontrib>SINGH KUMAR KAMLESH</creatorcontrib><creatorcontrib>KHERA BRIJ</creatorcontrib><creatorcontrib>NARODE SUNIL DNYANESHWAR</creatorcontrib><title>PROCESS FOR THE PREPARATION OF APIXABAN</title><description>A crystalline Form N-1 of apixaban substantially free from one or more of: 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; or methyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate, relative to apixaban by area percentage of HPLC and having a mean particle size equal to or greater than 100 μm.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFAPCPJ3dg0OVnDzD1II8XBVCAhyDXAMcgzx9PdT8HdTcAzwjHB0cvTjYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxocFGBoZmhibGFpYmjobGxKkCAGyeJLM</recordid><startdate>20160526</startdate><enddate>20160526</enddate><creator>DIWAKAR SANTOSH DEVIDAS</creator><creator>SUTHAR HITESHKUMAR NATWARLAL</creator><creator>SINGH KUMAR KAMLESH</creator><creator>KHERA BRIJ</creator><creator>NARODE SUNIL DNYANESHWAR</creator><scope>EVB</scope></search><sort><creationdate>20160526</creationdate><title>PROCESS FOR THE PREPARATION OF APIXABAN</title><author>DIWAKAR SANTOSH DEVIDAS ; SUTHAR HITESHKUMAR NATWARLAL ; SINGH KUMAR KAMLESH ; KHERA BRIJ ; NARODE SUNIL DNYANESHWAR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2016143894A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2016</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>DIWAKAR SANTOSH DEVIDAS</creatorcontrib><creatorcontrib>SUTHAR HITESHKUMAR NATWARLAL</creatorcontrib><creatorcontrib>SINGH KUMAR KAMLESH</creatorcontrib><creatorcontrib>KHERA BRIJ</creatorcontrib><creatorcontrib>NARODE SUNIL DNYANESHWAR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DIWAKAR SANTOSH DEVIDAS</au><au>SUTHAR HITESHKUMAR NATWARLAL</au><au>SINGH KUMAR KAMLESH</au><au>KHERA BRIJ</au><au>NARODE SUNIL DNYANESHWAR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR THE PREPARATION OF APIXABAN</title><date>2016-05-26</date><risdate>2016</risdate><abstract>A crystalline Form N-1 of apixaban substantially free from one or more of: 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid; 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; or methyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate, relative to apixaban by area percentage of HPLC and having a mean particle size equal to or greater than 100 μm.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US2016143894A1
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PROCESS FOR THE PREPARATION OF APIXABAN
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T07%3A49%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=DIWAKAR%20SANTOSH%20DEVIDAS&rft.date=2016-05-26&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2016143894A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true