PAN-HER ANTIBODY COMPOSITION

The present invention is directed to improved therapeutics against receptors within the EGFR/ErbB/HER family that more broadly interfere with multiple members of the HER family (pan-HER inhibition). More particularly, the invention is directed to the use of antibody compositions for human cancer the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PEDERSEN MIKKEL WANDAHL, CHRISTENSEN IDA K, LANTTO JOHAN, KRAGH MICHAEL, JACOBSEN HELLE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is directed to improved therapeutics against receptors within the EGFR/ErbB/HER family that more broadly interfere with multiple members of the HER family (pan-HER inhibition). More particularly, the invention is directed to the use of antibody compositions for human cancer therapy. In vitro studies have shown that the antibody compositions of the invention targeting multiple HER family receptors are superior to antibody compositions targeting only one HER family receptor.