METHOD FOR MANUFACTURING NEURAMINIC ACID DERIVATIVES

METHOD FOR MANUFACTURING NEURAMINIC ACID DERIVATIVES

A method for manufacturing a compound represented by the following formula (I): wherein R1 represents a C1-C19 alkyl, R2 represents a C1-C4 alkyl, and Ac represents an acetyl, wherein the compound of the formula (I) is optionally contained with up to 10 wt. % of a compound represented by the followi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: YAMAOKA MAKOTO, UMEO KAZUHIRO, WAKAYAMA MASAKAZU, NAKAMURA YOSHITAKA, MURAKAMI MASAYUKI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:A method for manufacturing a compound represented by the following formula (I): wherein R1 represents a C1-C19 alkyl, R2 represents a C1-C4 alkyl, and Ac represents an acetyl, wherein the compound of the formula (I) is optionally contained with up to 10 wt. % of a compound represented by the following formula (II): or a pharmacologically acceptable salt thereof, involving reacting a compound represented by the following formula (13): wherein R2 represents a C1-C4 alkyl and Ac represents an acetyl, with a compound represented by the formula R1C(OR7)3, wherein R1 represents a C1-C19 alkyl and R7 represents a C1-C6 alkyl, or a pharmacologically acceptable salt thereof.