Heterocyclic Ring and Carbocyclic Derivative

The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic effect, e.g. a compound of Formula (I): wherein R2 is a hydrogen atom or the like; ring A is five- to seven-cycloalkane or the like; C is a carbon atom; Q1 and Q2 are carbon atoms or the like; R9a and R9...

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Bibliographische Detailangaben
Hauptverfasser: HIRAMATSU YOSHIHARU, KAI HIROYUKI, TANAKA SATORU, NAKAMURA KEN'ICHIOH, NOZU AZUSA
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic effect, e.g. a compound of Formula (I): wherein R2 is a hydrogen atom or the like; ring A is five- to seven-cycloalkane or the like; C is a carbon atom; Q1 and Q2 are carbon atoms or the like; R9a and R9b are carbon atoms or the like; R6 is cycloalkyl or the like; R7 is a group represented by the formula: wherein ring D is benzene or the like; carbon atom a and b are carbon atoms; ring B is an aromatic carbocyclic ring or the like; s and s′ are 0 or the like; R9 and R9′ are halogen or the like, or the like, or its pharmaceutically acceptable salt.