Pharmaceutical Compositions and Administrations Thereof

The present invention relates to pharmaceutical compositions comprising a compound of Formulas I and II, optionally in combination with a Compound of Formula III and/or a Compound of Formula IV. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of u...

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Hauptverfasser: BOTFIELD MARTYN CURTIS, KAUSHIK RITU ROHIT, BINCH HAYLEY MARIE, KRAWIEC MARIUSZ, HURLEY DENNIS JAMES, SULLIVAN MARK JEFFREY, AREKAR SNEHA G, NUMA MEHDI, YANG XIAOQING, JOHNSTON STEVEN C, LUISI BRIAN, FANNING LEV TYLER DEWEY, SILINA ALINA, ZHANG YUEGANG, KADIYALA IRINA NIKOLAEVNA, MUDUNURI PRAVEEN, LEE ELAINE CHUNGMIN, GROOTENHUIS PETER DIEDERIK JAN, KESHAVARZ-SHOKRI ALI, MEDEK ALES, VAN GOOR FREDRICK F, ALARGOVA ROSSITZA GUEORGUIEVA, ZHANG BEILI, ZLOKARNIK GREGOR, ZAMAN NOREEN TASNEEM, SHETH URVI JAGDISHBHAI, YOUNG CHRISTOPHER RYAN, ALCACIO TIM EDWARD, VERWIJS MARINUS JACOBUS
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to pharmaceutical compositions comprising a compound of Formulas I and II, optionally in combination with a Compound of Formula III and/or a Compound of Formula IV. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis.