2,6,7 SUBSTITUTED PURINES AS HDM2 INHIBITORS

The present invention provides 2,6,7 substituted purines as described herein or a pharmaceutically acceptable salt thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods o...

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Bibliographische Detailangaben
Hauptverfasser: SUN BINYUAN, THOMPSON CHRISTOPHER FRANCIS, TROTTER B. WESLEY, MARTINEZ MICHELLE, REUTERSHAN MICHAEL HALE, CHRISTOPHER MATTHEW P, MACHACEK MICHELLE, VOSS MATTHEW E, FRADERA LLINAS FRANCESC XAVIER, SHIZUKA MANAMI, YANG LIPING
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides 2,6,7 substituted purines as described herein or a pharmaceutically acceptable salt thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.