Azaquinazoline Inhibitors Of Atypical Protein Kinase C

Azaquinazoline Inhibitors Of Atypical Protein Kinase C

The present application provides a compound of formula (I) and/or a salt thereof, wherein R1, G, and X are as defined herein. A compound of formula (I) and/or its salts have aPKC inhibitory activity, and may be used to treat proliferative disorders. Compositions comprising a compound of Formula (I)...

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Bibliographische Detailangaben
Hauptverfasser: OLOWOYE IKEOLUWA, DUGAN BENJAMIN J, MESAROS EUGEN F, OTT GREGORY R, ZULLI ALLISON L, DORSEY BRUCE D, MORRIS EMMA L, FOWLER KATHERINE M, MONCK NATHANIEL JT, SOUDY CHRISTELLE N, ZIFICSAK CRAIG A, PAVE GREGOIRE A, ROFFEY JONATHAN R.A, HUDKINS ROBERT L
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present application provides a compound of formula (I) and/or a salt thereof, wherein R1, G, and X are as defined herein. A compound of formula (I) and/or its salts have aPKC inhibitory activity, and may be used to treat proliferative disorders. Compositions comprising a compound of Formula (I) and/or a salt thereof are also provided.