Methods, Systems, and Compositions for Enrichment of Rare Cells

The present invention discloses a highly efficient method of isolating circulating tumor cells in a blood sample by removing leukocytes and other interfering components in a blood sample. Exemplary isolation method relies on a specially configured separation column for magnetic separation of leukocy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LIN HUNGIH, TSENG CHING-PING
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention discloses a highly efficient method of isolating circulating tumor cells in a blood sample by removing leukocytes and other interfering components in a blood sample. Exemplary isolation method relies on a specially configured separation column for magnetic separation of leukocytes from circulating tumor cells. Also disclosed are systems, devices, and reagents for performing the method, as well as diagnostic methods for early cancer detection, screening, and treatment monitoring utilizing the cell isolation method.