METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID

METHOD FOR THE SYNTHESIS OF ALPHA-AMINOALKYLENEPHOSPHONIC ACID

A method for the synthesis of alpha-aminoalkylenephosphonic acid or its phosphonate esters including the steps of forming a reaction mixture by mixing a P-O-P anhydride moiety including a compound, having one P-atom at the oxidation state (+III) and the other P-atom at the oxidation state (+III) or...

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Bibliographische Detailangaben
Hauptverfasser: COGELS SAMUEL, BURCK SEBASTIAN, NOTTE PATRICK
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:A method for the synthesis of alpha-aminoalkylenephosphonic acid or its phosphonate esters including the steps of forming a reaction mixture by mixing a P-O-P anhydride moiety including a compound, having one P-atom at the oxidation state (+III) and the other P-atom at the oxidation state (+III) or (+V), an aminoalkanecarboxylic acid and an acid catalyst, wherein the reaction mixture includes an equivalent ratio of alpha-aminoalkylene carboxylic acid to P-O-P anhydride moieties of at least 0.2, and recovering the resulting alpha-aminoalkylene phosphonic acid compound or an ester thereof from the reaction mixture.