MITOTIC KINESIN INHIBTORS AND METHODS OF USE THEREOF

MITOTIC KINESIN INHIBTORS AND METHODS OF USE THEREOF

This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the tr...

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Bibliographische Detailangaben
Hauptverfasser: ROBINSON JOHN E, ALLEN SHELLEY, VOEGTLI WALTER C, HANS JEREMY, LAIRD ELLEN, WALLACE ELI M, LYSSIKATOS JOSEPH P, ZHAO QIAN, DELISLE ROBERT KIRK, CORRETTE CHRISTOPHER P
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.