THIOLACTAMS AND USES THEREOF

THIOLACTAMS AND USES THEREOF

This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.

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Bibliographische Detailangaben
Hauptverfasser: GUO JIANPING, SOUCY FRANCOIS, REYNOLDS DOMINIC, BHARATHAN INDU T, DUFFEY MATTHEW O, ELDER AMY M, VOS TRICIA J, ZHU LEI, LI GANG
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.