THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES

The present invention relates to a thiol compound suitable for forming a chain of oligomers that can be grafted to an oligonucleotide. The invention also relates to an oligonucleotide grafted by such a compound, thus having one or more thiol functions, suitable for being immobilized on a gold surfac...

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Bibliographische Detailangaben
Hauptverfasser: FOURNIER-WIRTH CHANTAL, LEREAU MYRIAM, MEYER ALBERT, MAYEN JULIE, MORVAN FRANÇOIS, VASSEUR JEAN-JACQUES, FARRE CAROLE, CANTALOUBE JEAN-FRANÇOIS, CHAIX CAROLE
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to a thiol compound suitable for forming a chain of oligomers that can be grafted to an oligonucleotide. The invention also relates to an oligonucleotide grafted by such a compound, thus having one or more thiol functions, suitable for being immobilized on a gold surface or on a grafted surface.