SYSTEMS AND METHODS FOR BIOLOGICAL ION CHANNEL INTERFACES

Method for interfacing an integrated circuit with a biological ion channel, the integrated circuit being at least partially disposed within an electrolytic solution and including an amplifier and one or more electrodes on a surface thereof, includes forming one or more microwells proximate the one o...

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Bibliographische Detailangaben
Hauptverfasser: SHEPARD KENNETH L, RAMAKRISHNAN SIDDHARTH, ROSEMAN JARED, ROSENSTEIN JACOB
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Method for interfacing an integrated circuit with a biological ion channel, the integrated circuit being at least partially disposed within an electrolytic solution and including an amplifier and one or more electrodes on a surface thereof, includes forming one or more microwells proximate the one or more electrodes, applying a lipid membrane over the integrated circuit proximate the microwells, and placing a further electrode in the electrolytic solution proximate the lipid membrane on a side opposite the integrated circuit. A biological ion channel interface is also provided.