ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS

ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS

Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R8 and R9 are as defined herein. Methods associated with preparation and use of such compounds,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LINSELL MARTIN SHERINGHAM, GLIEDT MICAH JAMES, GOLDBLUM ADAM AARON, MOSER HEINZ ERNST, AGGEN JAMES BRADLEY, HILDEBRANDT DARIN JAMES, DOZZO PAOLA
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Beschreibung
Zusammenfassung:Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R8 and R9 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.