EXPANDED BED ADSORPTION METHODS FOR ISOLATION OF BASIC MILK PROTEINS INCLUDING LACTOFERRIN

The present disclosure relates to improved expanded bed adsorption processes for isolating proteins from milk sources. In particular embodiments, the present disclosure provides a process for isolating a milk protein, such as lactoferrin, from a milk source comprising establishing an expanded bed ad...

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Bibliographische Detailangaben
Hauptverfasser: ALVEY JOHN D, BANAVARA DATTATREYA, GONZALEZ JUAN M, PETERS JOSEPH ANDREW
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure relates to improved expanded bed adsorption processes for isolating proteins from milk sources. In particular embodiments, the present disclosure provides a process for isolating a milk protein, such as lactoferrin, from a milk source comprising establishing an expanded bed adsorption column comprising a particulate matrix, applying a milk source to the matrix, and eluting the lactoferrin from the matrix with an elution buffer comprising about 0.3 to about 2.0 M sodium chloride.