Fiber Optic Device for Sensing Analytes and Method of Making Same

Fiber Optic Device for Sensing Analytes and Method of Making Same

A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. A sensing element is attached to the distal end of an optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing eleme...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DENUZZIO JOHN D, SHERMAN DOUGLAS B, AMISS TERRY J, ALARCON JAVIER, WEIDEMAIER KRISTIN, JACOBSON ROSS W, PITNER J. BRUCE, HERDMAN CHRISTOPHER C
Format: Patent
Sprache:eng
Schlagworte:
DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
PHYSICS
SURGERY
TESTING
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Beschreibung
Zusammenfassung:A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. A sensing element is attached to the distal end of an optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing element further comprises at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the optical conduit and sensing element may be housed within a cannulated bevel.