Anti-Alpha Synuclein Binding Molecules

Provided are anti-human α-synuclein-specific binding molecules, e.g., antibodies or antigen-binding fragments, variants or derivatives thereof, as methods related thereto. Further provided are anti-human α-synuclein binding molecules which bind to specific N-terminal and C-terminal epitopes on human...

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Bibliographische Detailangaben
Hauptverfasser: GRIMM JAN, WEINREB PAUL, SU LIHE, NITSCH ROGER, HOCK CRISTOPH, WEIHOFEN ANDREAS
Format: Patent
Sprache:eng
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Zusammenfassung:Provided are anti-human α-synuclein-specific binding molecules, e.g., antibodies or antigen-binding fragments, variants or derivatives thereof, as methods related thereto. Further provided are anti-human α-synuclein binding molecules which bind to specific N-terminal and C-terminal epitopes on human α-synuclein. The binding molecules described herein can be used in pharmaceutical and diagnostic compositions for α-synuclein targeted immunotherapy and diagnosis, respectively.