Diamino-Pyridine, Pyrimidine, and Pyrazine Modulators of the Histamine H4 Receptor

Diamino-Pyridine, Pyrimidine, and Pyrazine Modulators of the Histamine H4 Receptor

Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H4 receptor modulators, and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruriti...

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Hauptverfasser: SAVALL BRAD M, DUNFORD PAUL J, TAYS KEVIN L, THURMOND ROBIN L, CAI HUI, CHAVEZ FRANK, QUIROZ JORGE A, GREENSPAN ANDREW J, ZHANG XIOAHU, WEI JIANMEI, MEDUNA STEVEN P, WOLIN RONALD L
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H4 receptor modulators, and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.