INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS

The inventive compounds are small molecule therapeutics that are potent inhibitors of Arginase I and II activity. The invention also provides pharmaceutical compositions of the inventive compounds and methods for using the inventive compounds for treating or preventing a disease or a condition assoc...

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Hauptverfasser: GOLEBIOWSKI ADAM, WHITEHOUSE DARREN, RYDER TODD, BECKETT RAYMOND PAUL, JI MIN KOO, VAN ZANDT MICHAEL
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creator GOLEBIOWSKI ADAM
WHITEHOUSE DARREN
RYDER TODD
BECKETT RAYMOND PAUL
JI MIN KOO
VAN ZANDT MICHAEL
description The inventive compounds are small molecule therapeutics that are potent inhibitors of Arginase I and II activity. The invention also provides pharmaceutical compositions of the inventive compounds and methods for using the inventive compounds for treating or preventing a disease or a condition associated with arginase activity.
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subjects ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
title INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS
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