MONOCLONAL ANTIBODY AGAINST INTERFERON-GAMMA (IFN-GAMMA) INDUCING FACTOR (IFIG, IL-18)

A protein which induces the IFN-γ production by immunocompetent cells and has a molecular weight of 19,000±5,000 daltons on SDS-PAGE or gel filtration method and a pI of 4.8±1.0 on chromatofocusing. The protein is isolated from mouse liver and can be purified by a monoclonal antibody specific to it....

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Hauptverfasser: TORIGOE KAKUJI, OKAMURA HARUKI, TANIMOTO TADAO, TANIGUCHI MUTSUKO, KURIMOTO MASASHI, KOHNO KEIZO, KUNIKATA TOSHI
Format: Patent
Sprache:eng
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Zusammenfassung:A protein which induces the IFN-γ production by immunocompetent cells and has a molecular weight of 19,000±5,000 daltons on SDS-PAGE or gel filtration method and a pI of 4.8±1.0 on chromatofocusing. The protein is isolated from mouse liver and can be purified by a monoclonal antibody specific to it. The monoclonal antibody can be also used for assaying the protein.