Methods for synthesizing molybdopterin precursor Z derivatives

Methods for synthesizing molybdopterin precursor Z derivatives

Provided herein are synthetic methods for preparing a compound of formula (I): Also provided herein are synthetic methods for preparing a compound of formula (XIII): The disclosure also provides useful intermediates, derivatives, prodrugs, and pharmaceutically acceptable salts, solvates and hydrates...

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Hauptverfasser: WATT DEREK KEVIN, PROISY NICOLAS GEORGES RENE, LONG XIANGTIAN, DAI DANMEI, LITTLE GILLIAN MARY, CLINCH KEITH, BAARS SYLVIA MYRNA, DIXON RACHEL ANNE, BRUNNER ANDREAS, LANDREAU CYRILLE ABEL SÉBASTIEN
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Provided herein are synthetic methods for preparing a compound of formula (I): Also provided herein are synthetic methods for preparing a compound of formula (XIII): The disclosure also provides useful intermediates, derivatives, prodrugs, and pharmaceutically acceptable salts, solvates and hydrates of the formula (I) and formula (XIII) compounds. These compounds are useful for treating diseases associated with molybdenum cofactor deficiency.