PRODUCTION OF ISOPROPANOL BY IMPROVED RECOMBINANT STRAINS

The expression vector includes: the nucleic acids coding for the polypeptides forming a polypeptide complex having an enzyme activity allowing acetoacetyl-CoA to be converted to acetoacetate; optionally, at least one nucleic acid coding for a polypeptide having an enzyme activity allowing acetoaceta...

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Bibliographische Detailangaben
Hauptverfasser: CLEMENT BENJAMIN, MARCHAL REMY, COLLAS FLORENT, CLAASSEN PIETERNEL A.M, LOPEZ CONTRERAS ANA MARIA
Format: Patent
Sprache:eng
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Zusammenfassung:The expression vector includes: the nucleic acids coding for the polypeptides forming a polypeptide complex having an enzyme activity allowing acetoacetyl-CoA to be converted to acetoacetate; optionally, at least one nucleic acid coding for a polypeptide having an enzyme activity allowing acetoacetate to be converted to acetone; and at least one nucleic acid coding for a polypeptide having an enzyme activity allowing acetone to be converted to isopropanol; the expression of the nucleic acids being controlled by a single constitutive promoter located upstream of the abovementioned nucleic acids.