PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS

Compounds of Formula (I) and pharmaceutically acceptable salts thereof in which X1, X2, X3, L, R3, R4, R5, R7 and n have the meanings given in the specification, are modulators of GPR119 and are useful in the treatment or prevention of diseases such as, but not limited to, type 2 diabetes, diabetic...

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Hauptverfasser: HINKLIN RONALD JAY, TURNER TIMOTHY M, PRATT SCOTT, FELL JAY BRADFORD, FISCHER JOHN PETER, CONDROSKI KEVIN RONALD, BENSCIK JOSEF ROLAND, AICHER THOMAS DANIEL, SINGH AJAY, BOYD STEVEN ARMEN
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creator HINKLIN RONALD JAY
TURNER TIMOTHY M
PRATT SCOTT
FELL JAY BRADFORD
FISCHER JOHN PETER
CONDROSKI KEVIN RONALD
BENSCIK JOSEF ROLAND
AICHER THOMAS DANIEL
SINGH AJAY
BOYD STEVEN ARMEN
description Compounds of Formula (I) and pharmaceutically acceptable salts thereof in which X1, X2, X3, L, R3, R4, R5, R7 and n have the meanings given in the specification, are modulators of GPR119 and are useful in the treatment or prevention of diseases such as, but not limited to, type 2 diabetes, diabetic complications, symptoms of diabetes, metabolic syndrome, obesity, dyslipidemia, and related conditions.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS
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