PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS

PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS

Compounds of Formula (I) and pharmaceutically acceptable salts thereof in which X1, X2, X3, L, R3, R4, R5, R7 and n have the meanings given in the specification, are modulators of GPR119 and are useful in the treatment or prevention of diseases such as, but not limited to, type 2 diabetes, diabetic...

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Bibliographische Detailangaben
Hauptverfasser: HINKLIN RONALD JAY, TURNER TIMOTHY M, PRATT SCOTT, FELL JAY BRADFORD, FISCHER JOHN PETER, CONDROSKI KEVIN RONALD, BENSCIK JOSEF ROLAND, AICHER THOMAS DANIEL, SINGH AJAY, BOYD STEVEN ARMEN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Compounds of Formula (I) and pharmaceutically acceptable salts thereof in which X1, X2, X3, L, R3, R4, R5, R7 and n have the meanings given in the specification, are modulators of GPR119 and are useful in the treatment or prevention of diseases such as, but not limited to, type 2 diabetes, diabetic complications, symptoms of diabetes, metabolic syndrome, obesity, dyslipidemia, and related conditions.