Genetic Test for the Identification of Carriers of Complex Vertebral Malformations in Cattle

Genetic markers for identifying bovine carriers of complex vertebral malformation (CVM) disease gene are described. The genetic markers, including the microsatellite markers BM4129, INRAA003, BMS2790, ILSTS029, INRA123, BM220, HUJ246, BMS862, BMS937, BL1048, BMS2095 and BMS1266 and the bovine SLC35A...

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Hauptverfasser: THOMSEN BO, JEPPESEN METTE, NIELSEN BIRTE VIVI HUNNICKE, SVENDSEN SOREN, PANITZ FRANK, JENSEN HELLE, JONKER MARC SSERGIJ, HOJ ANETTE, HORN PER, BENDIXEN CHRISTIAN, PEDERSEN ANDERS AASBERG, HOLM LARS-ERIK
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Sprache:eng
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Zusammenfassung:Genetic markers for identifying bovine carriers of complex vertebral malformation (CVM) disease gene are described. The genetic markers, including the microsatellite markers BM4129, INRAA003, BMS2790, ILSTS029, INRA123, BM220, HUJ246, BMS862, BMS937, BL1048, BMS2095 and BMS1266 and the bovine SLC35A3 gene, are located on bovine chromosome BTA3. The G/T polymorphism at position 559 of the bovine SLC35A3 gene is identified as being causative and diagnostic for CVM in cattle.