Aspart Proinsulin Compositions and Methods of Producing Aspart Insulin Analogs

Aspart modified proinsulin sequences that have a modified C-peptide amino acid and/or nucleic acid modification for producing aspart insulin analogs are provided. Highly efficient processes for preparing the aspart insulin analogs and improved preparations containing the aspart insulin analogs prepa...

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Hauptverfasser: STOKELL DAVID J, ZIMMERMAN RONALD E, AKERS MICHAEL P
Format: Patent
Sprache:eng
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Zusammenfassung:Aspart modified proinsulin sequences that have a modified C-peptide amino acid and/or nucleic acid modification for producing aspart insulin analogs are provided. Highly efficient processes for preparing the aspart insulin analogs and improved preparations containing the aspart insulin analogs prepared according to the methods described herein are also provided.